
Clinical evaluation of new CAR-T therapy
In recent years, chimeric antigen receptor (CAR) T-cell therapy for hematological malignancies has become a major breakthrough in cell therapy. To date, the U.S. Food
In recent years, chimeric antigen receptor (CAR) T-cell therapy for hematological malignancies has become a major breakthrough in cell therapy. To date, the U.S. Food
Antibody-drug conjugates (ADCs) have achieved remarkable efficacy in cancer treatment and have attracted worldwide attention. Although ADCs pose significant challenges to researchers, especially in identifying
The transcription factor family consists of c-MYC, L-MYC and N-MYC, which are the main regulators of cellular processes such as cell proliferation, cell differentiation, cell
Protein-polymer conjugates are widely used as disease therapeutics and have advantages such as high target specificity. but their use also faces some challenges: rapid clearance
We are not unfamiliar with vaccines, but few people know about vaccine adjuvants. The so-called adjuvant refers to the substance added to the vaccine that
Antibody-dependent cell-mediated cytotoxicity (ADCC) is a potent mechanism of cytotoxicity, mainly mediated by natural killer (NK) cells. When specific antibodies bind to the targeted cell
Tumor markers (TM) refer to the synthesis and secretion of tumor cells and gene expression during the occurrence and proliferation of malignant tumors, or the
On November 10, when AstraZeneca announced its third-quarter 2022 results, it also announced that it would not submit a listing application for the new crown
A COVID-19 vaccine based on mRNA technology has changed the landscape of the human battle against the SARS-CoV-2 virus. Comirnaty (BNT162b2), developed by pharma giant
On November 8, GlaxoSmithKline (GSK) announced that the phase IIb clinical results of the antisense oligonucleotide bepirovirsen in the treatment of chronic hepatitis B will
The excellent efficacy of targeted drugs and the inevitable problem of drug resistance have been in a state of ebb and flow. Researchers continue to
Antibodies of ADC drugs are antibodies targeting tumor cell antigens, which are linked to small-molecule drug poisons through linkers to kill tumor cells and surrounding